Simona Kijonková is in business since 2008. At the beginning, she worked within IT company, where she participated in the development of hundreds of web designs and e-shops. In 2015, she was listed within the prestigious ranking "Top 25 Czech women in business of 2015" for her entrepreneurial and innovative activities. In 2016, she was established as one of the 75 most influential women of the Czech Republic by prestigious magazine Forbes.

In addition to Zásilkovna.cz company, she is also engaged in her IT company MYPS s.r.o., which develops web tailor-made applications. Furthermore, she is actively interested in angel investing into various technological start-ups; e.g. SizeID.com, revolutionary application that helps customers to choose the right size of clothing while shopping online; and Robeeto.com, a P2P community platform which mediates various services online.