Mimoza Kusari-Lila became part of public service in 2003 when she has been offered the position of spokeswomen and Adviser to Prime Minister of Kosovo, Bajram Rexhepi. 

 Mimoza Kusari-Lila served as executive director of the American Chamber of Commerce in Kosovo (AmCham), from 2006 to 2009.

.Mimoza Kusari-Lila became active member of Kosovo politics in the elections of 2009, running for the major of Gjakova municipality and nearly won.

Ms. Kusari – Lila was nominated and approved as the Deputy Prime Minister for Economy and Minister of Trade and Industry, a position which she held since February 2011 until October 2013.

In December of 2013, Mimoza Kusari-Lila has run for the second time as a candidate for Mayor of Gjakova. She won the elections and became the first and only female mayor in Kosovo.